Research groups

Structural Informatics & Network Biology (SB&NB)

Research in this lab mainly focuses on understanding the molecular bases of how macromolecular complexes and cell networks operate by analyzing protein-protein interaction networks with the help of high-resolution 3D structures. Proteins seldom act alone performing their tasks and most biological processes are carried out by macromolecular assemblies and regulated through a complex network of protein-protein interactions. Thus, modern molecular and cell biology no longer focus on single macromolecules but now look into complexes, pathways or even entire organism interactomes.

The emerging field of systems biology is now mainly centered on unraveling the relationships between the components present in an organism and trying to use the information that they contain to boost novel biomedical applications. Accordingly, in this group, we have established two interrelated research lines devoted to reveal the molecular bases of how macromolecular complexes and cell networks operate.

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Institutions

Bioinformatics expertise:

Group Leader:

Patrick Aloy