A research team has studied the efficacy of new CHO/PA polymeric nanoparticles for the sustained delivery of a drug used in breast cancer therapy. Some of the experiments have been carried out in the NCD-SWEET beamline at ALBA.
News and events
The Conference "The opportunity for Big Data and Artificial Intelligence in clinical decision-making and health evaluation" held in Barcelona, on November 6th, 2019, was organized by Bioinformatics Barcelona (BIB), the Faculty of Medicine and Health Sciences of the University of Barcelona (UB) and professional societies.
For centuries, quinoline has been an effective compound in antimalarial drugs, although no one knew its mode of action in vivo. A team led by the Weizmann Institute has discovered its mechanism in infected red blood cells in near-native conditions, by usi
Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD), in collaboration with researchers from the Institut de Robòtica i Informàtica Industrial, have developed an artificial intelligence system to help diagnose rare diseases related to deficienc
El 19 de septiembre en el Movistar Centre de Plaza de Catalunya (Barcelona)
Avocados, the green gold in worldwide agriculture. The avocado genome has been sequenced by an international team in which the researchers Julio Rozas and Alejandro Sáncez-Gracia, from the Faculty of Biology and the Biodiversity Research Institute of the
Dysdera sylvatica: a ravening predator in the Canary laurel forests. A research team of the Faculty of Biology and the Biodiversity Research Institute (IRBio) of the University of Barcelona has sequenced the genome of the spider Dysdera silvatica Schmidt
Researchers from the UPF, IMIM and UVIC have developed the website GUILDify to study the molecular environment of the proteins involved in diseases.
Researchers from the Institute of Biotechnology and Biomedicine (IBB), in collaboration with scientists from the University of Warsaw recently presented an important update to their AGGRESCAN 3D computational method, focused on facilitating and reducing the cost of developing new generation protein-based drugs, diminishing their propensity to form aggregates and keeping them stable and active for a longer period of time.
A research team has presented the first stable simulations of DNA crystals, according to a study published in the journal Chem -part of the publisher Cell- and led by Modesto Orozco, Professor from the Department of Biochemistry and Molecular Biomedicine
Opening new pathways for the treatment of cancer - Glioblastoma is a type of brain tumor with no cure, usually associated with mutations in the epidermal growth factor receptor (EGFR). The main EGFR mutation found in this tumor -known as EGFRvlll- is...
Researchers at the CRG, GRIB (UPF-IMIM) and Helmholtz Center have discovered a new mechanism controlling the expression of a set of genes important for cell proliferation and tumour progression.
The eTRANSAFE (Enhancing TRANslational SAFEty Assessment through Integrative Knowledge Management) project aims at enhancing the efficiency of translational safety assessment during the drug discovery and development process by means of the development of an integrative data infrastructure and innovative computational methods and tools.
An international team led by computational biologist Fran Supek at IRB Barcelona develop a machine learning method to predict unknown gene functions of microbes.
The Proximal pathway Enrichment Analysis method can be applied to reuse drugs targeting mechanisms shared by different diseases, such as Alzheimer’s and type 2 diabetes.
The inauguration of the interuniversity doctoral program took place in the auditorium of the Faculties of Sciences and Biosciences of the Universitat Autònoma de Barcelona (UAB) on June 20, 2018.
A study published in Nature Medicine by a team led by researchers at the Spanish National Cancer Research Centre (CNIO), with the participation of Mind the Byte, shows that the administration of silibinin in patients with brain metastasis reduces lesions without causing any adverse effects.
Les propostes es poden presentar fins el 25 de juny
Researchers of the Institute of Biotechnology and Biomedicine (IBB-UAB) have achieved to generate 4 peptides -molecules smaller than proteins - capable of self-assembling in a controlled manner to form nanomaterials.
A new study led by researchers at Pompeu Fabra University and Hospital Clínic proposes different approaches to the study of a rare disease.
Attendees discussed the recent advances in information technologies that are facilitating translational research and precision medicine.
The Doctorate Program in Bioinformatics, involving UAB, UPC, UdG, UdL, UOC and UVic-UCC and promoted by the BIB, had its first internal workshop at Casa de Convalescència on April 4th 2018.
Today, Cell journal is publishing the results of the largest cancer project in the world, which studies 33 types of tumour using genomic data from 11,000 patients.
Save the Date: 24.10.2018, CosmoCaixa Barcelona
The “Google” of human genetic variation
The deal enables Mind the Byte, a pioneer in developing cloud technologies for computational drug design, to secure its leadership on the Spanish market and furthers its plans to become one of the key companies in the industry in Europe
Researchers from GRIB (IMIM-UPF) have analysed the genome of 68 mammals, including our own species
Together, the two companies will provide a broad portfolio of in silico models covering most aspects of virtual drug discovery and development. Prosilico software will now be included in Mind the Byte's SaaS platform and both firms will promote each other's technologies.
20 world leaders in 3D genomics will meet today until Wednesday in Barcelona at the Barcelona BioMed Conference organized by IRB Barcelona and the BBVA Foundation.
A study published by IRB Barcelona in Nature Genetics demonstrates that the error (mutation) surveillance and repair system shows greater efficiency in the protein-coding regions of genes.
A new pedagogical and communicative tool for the youngest audience
The European project "BioS - Digital skills on Computational Biology for Health Professionals" has been awarded with 1 million euro for the period 2018-2020 within the Erasmus+ Sector Skills Alliances in vocational education and training key action.
The Hospital del Mar Medical Research Institute (IMIM) and the Pompeu Fabra University (UPF) have just published a comment in the prestigious journal Nature Reviews Drug Discovery where they explain the excellent results from eTOX, a project that has facilitated a new model for collaboration among pharmaceutical companies, as well as between these and academia, where data and knowledge are shared for the purposes of improving the toxicological evaluation of drugs.
May we inform you that the interuniversity Doctorate Program in Bioinformatics is already running and that preregistration is open until November 15th.
The Graduate Diploma in Big Data Processing for Life Sciences, which will begin this year's edition on 20 October at the Universitat Autònoma de Barcelona (UAB), has opened its enrolment process.
S'han graduat nou alumnes de l'Institut Provençana de l'Hospitalet de Llobregat i dos del centre Gimbernat Formació de Sant Cugat del Vallès L'objectiu del cicle és formar tècnics informàtics amb coneixements en ciències de la vida que els capaciti per entendre els conceptes bàsics i les eines bioinformàtiques més comunes utilitzades en el sector El dijous 14 de setembre ha tingut lloc l'acte de lliurament de diplomes a la primera promoció de graduats del cicle de grau superior de Desenvolupament d'Aplicacions Web, adaptat al perfil professional de Bioinformàtica.
The five-year project eTRANSAFE: Enhancing Translational Safety Assessment through Integrative Knowledge Management, aims to develop an advanced data integration infrastructure together with innovative computational methods to improve the security in drug development process and is funded by the Innovative Medicines Initiative (IMI 2) together with the pharmaceutical industry.
L'Auditori Pompeu Fabra de la seu dels Enginyers Industrials Catalunya ha acollit el dimarts 11 de juliol un workshop gratuït organitzat per l'Associació Bioinformatics Barcelona (BIB) i el Col·legi Oficial d'Enginyeria en Informàtica de Catalunya (COEINF).
A team of researchers led by the lecturer Manel Esteller, ICREA researcher in the Bellvitge Biomedical Research Institute (IDIBELL) and the Faculty of Medicine and Health Sciences of the University of Barcelona, have characterized the complete epigenomes of the most common tumours, among which are the ones from colon cancer, lung cancer and breast cancer.
Scientists from the Computational Biophysics group of GRIB (IMIM-UPF) jointly with Freie Universität Berlin (FU Berlin), for the first time, simulated the association and dissociation of protein molecules in atomic detail.
Vocational Education and Training (commonly known as VET) in bioinformatics is sure to be a way for many young people to enter the job market and a good gateway to companies in the healthcare and life sciences sector looking to add junior technicians to their teams, not just PhDs.
p38α is a protein involved in chronic inflammatory diseases and cancer, among other pathological conditions. Published in the journal eLife, the study provides a deeper understanding of the structure of this protein, thereby paving the way for the development of more effective inhibitors.
Made of Genes, a personal genomics start-up based in Barcelona (Spain) whose beginnings lie in ESADE Business School (both BIB members), has been selected to join the 2nd edition of the Dubai Future Accelerators program, an initiative of the Dubai Future Foundation.
His appointment confirms the centre’s commitment to personalized medicine as an area of future development for supercomputing.
When 18,000 years ago humans entered America through the Bering Strait they found a totally different climate and food. A recent study published in the journal Proceedings of the National Academy of Sciences USA (PNAS) shows that this migration left traces in the genome of Native Americans, descendants of those early settlers.
May be key in central nervous system diseases such as Alzheimer's
Educational and economic levels of the analyzed countries are highly related to the practice of physical activity of their citizens.
Predictive models of diseases are gaining importance in medicine thanks to their usefulness when customizing treatments. Hence, computational methods based on human biology have become a key factor for the development of customized medicine.
BSC encourages researchers to submit their papers.
An international consortium depicts the genetic and molecular evolution of insectivorous plants
Natural selection favours fragile and unhealthy old age if it is due to mutations that are beneficial during childhood. As of 40-50 years of age, natural selection is blind because we have already passed on our genes, whether beneficial or not, to our descendants.
Scientists at the IBE find common features in genes associated with diseases. The study, published in the journal Human Molecular Genetics, suggests a degree of biological importance in the genome depending on the linkage of genes to disease
'Rare Disease Discovery’ is a prototype that automatically ranks the rare diseases that are most likely associated to a list of patient symptoms. The prototype shows a precision of moret han 80% on the benchmark tests
Enrolment is open for the Graduate Diploma in Big Data Processing for Life Sciences offered by the Universitat Autònoma de Barcelona. This new programme will begin on 17 February and is offered in collaboration with several institutions, such as Fundació i2cat, Hospital Sant Joan de Déu, IDIAP Jordi Gol, Consorci Hospitalari Parc Taulí and the Centre for Genomic Regulation (CRG).
The first predictive bioinformatics tool that automatically analyzes mass transcriptomic data from the genome of any species, generated by new generation sequencing technologies, providing a complete report in less than 24 hours
Researchers of the Computer Vision and Robotics Institute (ViCOROB) of the University of Girona (UdG) obtained the best results in the international competition entitled "MS segmentation challenge using a data management and processing infrastructure".
The objective of this initiative by the Obra Social de la Caixa and Caixa Capital Risc is to drive a transformation of scientific knowledge in companies
A bioinformatics analysis of pairing 64 drugs used to treat breast cancer allows researchers at IRB Barcelona to identify 10 previously untested combinations with potential to tackle resistance to breast cancer treatment. In spite of the many drugs avail
L'esdeveniment se celebrarà el 20 de desembre a l'auditori del Parc de Recerca Biomèdica de Barcelona (PRBB). L'organitzen l'associació Bioinformatics Barcelona (BIB) i la Societat Catalana de Biologia (SCB), filial de l'Institut d'Estudis Catalans (IEC).
New perspectives for the inhibiting drug designs for the drug-resistant influenza A virus
A new image processing program applicable to all study fields that require characterization of image contour
Sequentia Biotech, based at the Barcelona Science Park, recently developed Gaia, an online bioinformatics tool able to manage and analyze metagenomic data from any microbial community (bacteria, viruses and eukaryotes) generated by Next Generation Sequencing technologies (NGS) applied to human, animal and plant genetics.
AdaptNET will drive the collaboration of the research teams in evolutionary genomics and will promote dissemination of scientific advances to all society
Two research groups of the Research Programme on Biomedical Informatics (GRIB) participate in the EU-ToxRisk project coordinating the application of computational methods
Computational biologists, Núria López-Bigas and Fran Supek will lead new groups
The Civil Order of Alfonso X the Wise is conferred onto people and entities with a distinguished trajectory in education, research and/or culture by the Spanish Ministry of Education,Culture and Sport.
New bioinformatics tool to develop molecule markers à la carte out of genomic data
Bioinformatics Barcelona boosts its digital presence to become the meeting point for the bioinformatics community. The BIB website details the bioinformatic activities of 40 partners and over 80 research groups.
The effectiveness of antiretroviral drugs used to treat HIV (human immunodeficiency virus) is frequently affected by the virus' ability to develop genetic mutations.
The conference took place at the University of Copenhagen on April 26-27, bringing together 150 experts in the area.
Come to the information session of the master's degree in Bioinformatics for Health Sciences on April the 8th at 17:00. The aim of this session is to provide information about the main characteristics of the Master, which is available for the 2016-2017 academic year.
The work has been carried out using latest-generation molecular simulations. The results will, in the future, enable new therapeutic pathways.
The great bioscientific challenge of today is to manage and operate flexibly the deluge of scientific data which are currently available.
L'associació BIB compta amb 25 entitats membres entre universitats, centres de recerca, instituts de recerca hospitalària, grans infraestructures científiques, empreses i altres institucions, a més de 23 entitats en procés d'incorporació.
L'adaptació curricular d'un cicle formatiu al perfil bioinformàtic cobrirà la necessitat de tècnics bioinformàtics dels sectors industrial, sanitari i de recerca.
La plataforma Bioinformatics Barcelona (BIB) ha presentat aquest matí el seu Pla Estratègic, en un acte presidit per Antoni Castellà, secretari d'Universitats i Recerca, a CaixaForum Barcelona.
One of its objectives is to turn the Barcelona area into an international point of reference in the field of bioinformatics, based on its scientific excellence and resources.