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Genetic signature of natural selection in first Americans

When 18,000 years ago humans entered America through the Bering Strait they found a totally different climate and food. A recent study published in the journal Proceedings of the National Academy of Sciences USA (PNAS) shows that this migration left traces in the genome of Native Americans, descendants of those early settlers.

The fundamental causes of human ageing explained

Natural selection favours fragile and unhealthy old age if it is due to mutations that are beneficial during childhood. As of 40-50 years of age, natural selection is blind because we have already passed on our genes, whether beneficial or not, to our descendants.

Key genes for disease

Scientists at the IBE find common features in genes associated with diseases. The study, published in the journal Human Molecular Genetics, suggests a degree of biological importance in the genome depending on the linkage of genes to disease