Full-stack Developer to incorporate within the EUCANCan project
- Centre / Institution:
- Bellvitge Biomedical Research Institute
- Bioinformatics expertise:
- Biomedical Informatics
The global aim of the EUCANCan project is to build a network of Personalized Medicine nodes that enables and promotes the generation, exchange, and sharing of harmonized and high-quality genomic and clinical data. This offer is supported by the European Union's Horizon 2020 research and innovation program under grant agreement No 825835.
IDIBELL is a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB) and the Viladecans Hospital (HV), located in south Barcelona.
The research focuses of IDIBELL are cancer, neuroscience, and translational medicine; research, innovation, and society are the pivots on which researchers work every day in order to improve the quality of life of citizens.
IDIBELL is located in L'Hospitalet de Llobregat, south of Barcelona. It is a member of the Campus international Excellence of the University of Barcelona HUBc and part of the CERCA institution of the Generalitat of Catalonia. In 2009, it became one of the First Uve Spanish research centers accredited as a health research institute by the Carlos III Institute of Health. More recently, the European Commission has recognized IDIBELL with the HRS4R logo (Excellence in Human Resources in Research), which identiUesIDIBELL as a provider and supporter of a stimulating research work environment.
With the deployment of massively parallel next-generation sequencing (NGS) technologies, the theidentiUcation of variants of unknown significance (VUS) in cancer-predisposing genes is expanding dramatically. Our group has worked on the classification of hereditary cancer genes VUS identified in the Spanish population, pioneering the development of functional algorithms and the refinement of gene-specific classification guidelines. There is a real need to build resources that facilitate the interpretation and classiUcation of VUS taking into account geographical genetic specialties. Data storage and data sharing, both at the national and international level, are critical to effectively mine the huge amounts of information obtained during genetic testing.
We are seeking a database software engineer / full-stack developer who will implement a project aimed at creating a national registry of genetic variants in cancer-predisposing genes that could be useful for their interpretation. To address this issue, the candidate will be responsible for the design and development of a web-based platform, including the whole system: front-end, back-end, and a relational database of genetic variants. specific data loading subsystems will be developed for collaborator groups allowing for partial automation. Loaded variants will be annotated using a bioinformatic pipeline. The system will have a variant classification module to help data curators evaluate pathogenicity. Finally, the necessary mechanisms to push the variants to international variant databases will be implemented.
The candidate will have the opportunity to work within the Hereditary Cancer Group at IDIBELL (www.idibell.cat/en/content/hereditary-cancer) under the supervision of Dr. Gabriel Capellá and ConxiLázaro. The overarching goal of the Hereditary Cancer Group at IDIBELL
is to gain insight into the molecular basis of hereditary cancer, to personalize risk assessment to patients and relatives, as well as to individualize management regarding follow-up, treatment, and prophylactic measures. Our multidisciplinary group includes basic researchers, clinicians, bioinformaticians, genetic counselors in familial cancer and laboratory technicians, facilitating fully comprehensive studies, data analysis, access to the patients and samples, and the translation of the obtained results to the clinics and genetic counseling.
Successful candidates will join a dynamic, young, and well-equipped research group with strong interactions and multidisciplinary research. The group offers a stimulating research atmosphere and an environment in which collaboration and exchange of ideas and techniques are actively encouraged with a strong commitment to research which provides a lively and stimulating environment for young talents.
Desired skills and expertise
Computer science or related degree.
The applicant must have at least 2 years of work experience as full-stack developer(front-end, back-end, and database). Experience in multiple programming languages is alsorequired. Knowledge or working experience about genetics and NGS pipelines will be essential.
Good working knowledge of Linux. Experience dealing with sensible data andknowledge of security best practices. Fluent in R programming.
Excellent communication skills, both written and oral, and ability to collaborate with teammembers.
Excellent organizational skills.
Ability to work independently as well as part of a team.
3-5 years of working experience as full-stack developer.
Working experience in Django web framework and PostgreSQL.
Any participation in research projects, co-authorship in publications and mobility experience will beconsidered as a valuable contribution.
Contract duration and other benefits
Type of contract: Temporary (1 year)
Workday: Full-time, 40h / week
Working hours: Monday to Friday, Vexible schedule
Professional Category: Informatic Technician B
Salary: According to IDIBELL salary tables
Job location: IDIBELL laboratory
Incorporation: Immediate hiring.
Other: "This contract is supported by the National Cancer Institute of the National Institutes ofHealth under Award Number R01CA218342."
Required information and contact