Postdoctoral position at the GCAT LAB

Deadline:
30/06/2020
Centre / Institution:
Institute for Health Science Research Germans Trias i Pujol
Bioinformatics expertise:
Computational Genomics

Job description

The Institute of Health Germans Trias I Pujol (IGTP) is a center of excellence of the Institute of the Spanish National Health Institute (ISCIII) located in Badalona. IGTP research is translational medicine institute focused on the processes and mechanisms and on understanding disease and its translation to patients. The Institute is associated with one of the great teaching hospitals in the Barcelona area: the Germans Trias i Pujol Hospital (HUGTP) and is part of the Can Ruti biomedical campus. In addition, it is a CERCA center and a member of the Biocluster supported and supervised by the Government of Catalonia.

Description Group

GCAT lab focuses on understanding how genes and environment modulate disease in human populations. Towards this end, we combine epidemiologic and OMIC approaches in a large population based cohort with detailed to genomic analyses to identify and characterize genetic architecture underlying common diseases susceptibility and evolution.

Research Project

The postdoctoral researcher will be part on a project that aims at understanding the genetic basis of multimorbidity and disease trajectories in human populations. Identifying the genomic impact on disease trajectories is a growing field of research. Advances in high-throughput technologies and mining of electronic Health Records allow us to identify and characterize in a dynamic manner the impact of genetic profiles in susceptibility and prognosis of common disease with a wide perspective.

Most of our knowledge so far comes from the analysis of one disease or trait giving us a partial scenario of human disease, multi morbid approach and temporary trajectories are largely ignored until now. Our laboratory is at the forefront of the research aimed at elucidating the contribution genetics to human disease load. We are experts in genomics and molecular epidemiology.

In this project, we will apply our proven expertise in these research fields to elucidate the role of genetic profiles on temporary disease trajectories in a large cohort. Identification of disease trajectories and common comorbidity patterns is highly relevant because it has direct consequences for the ability to treat diseases in an accurate manner. We are using mining approaches in temporary health registers to generate strong patterns that allow us to look for molecular signatures using genomic variation to get a comprehensive overview of the impact of personal genetic profile in disease.

Desired skills and expertise

Duties

The postdoctoral researcher will be responsible for the analysis of health registers, to develop, and study patterns of disease in the context of common diseases susceptibility. Among others, the tasks involved in the postdoctoral research project will be identifying signatures of diseases trajectories, identifying evidence of genetic impact on it, and looking for associations between genetic and environmental variables in the disease. The researcher will be in charge of a PhD student involved directly in the project.  

Candidate requisites

A PhD in Biology or a related field, good organizational skills, and good writing skills are required. Previous professional experience will be considered.

Contract duration and other benefits

What do we offer?

We offer a full-time contract. Salary will depend on the experience of the candidate. Partial-time tele-working. The candidate will join a research with three PhD students. The lab is leading the GCAT project which offers an extensive networking of opportunities.

Required information and contact

Application process

Please send your CV (including the contacts of potential references) and a brief letter of motivation to: rdecid(ELIMINAR)@igtp.cat. Please include "GCAT_VEIS" in the subject of your e-mail.

Application deadline: 30th June 2020.