PhD Position in Cancer Genomics

Centre / Institution:
Institute for Research in Biomedicine (IRB Barcelona)
Bioinformatics expertise:
Biomedical Informatics, Computational Genomics
Cancer Genomics, DNA damage and repair

Job description

The successful candidate will work on the project Genome-wide DNA damage and repair to understand mutational processes in tumors (DamReMap) (Ref. RTI2018-094095-B-I00, PI Dr. López-Bigas), and will be focused on the characterization of mechanisms of DNA damage and mutagenesis after treatment of human cell lines with chemotherapeutic drugs. This will allow to compute genome-wide models of damage and repair, which can be compared to sequencing data from tumors and allow identification of mutations and genomic elements promoting chemotherapy resistance.

The project includes both experimental (generation of maps of damage) and computational (analysis of the maps) work. Therefore, candidates with either or both profiles/interests are welcome to apply.

The thesis will be directed by Prof. Núria López-Bigas, PI of the Biomedical Genomics lab.

Desired skills and expertise

Grade with outstanding qualifications in biology, biochemistry, bioinformatics, chemistry or similar.

Contract duration and other benefits

The selected candidate will need to apply for the call of the Ministerio de Ciencia, Innovación y Universidades Ayudas para contratos predoctorales para la formación de doctores 2018, to be published in September 2019.

Required information and contact

Applicants should send their CV + motivation letter to Martina Gasull (irbjobs(ELIMINAR)

​Selection process: Candidates will be selected exclusively on merit, on the basis of their curricula.