Two Postdoctoral Positions in Bioinformatics/Multi-omics of Autoimmune Diseases

Deadline:
30/11/2017
Centre / Institution:
Vall d'Hebron Institute of Research
Bioinformatics expertise:
Bioinformatics of Disease and Treatment
Keywords:
NGS

Job description

Two postdoctoral research opportunities are available at the Vall d'Hebron Research Institute (VHIR) in Barcelona, Spain, in the autoimmune disease research laboratory of Dr Antonio Julià.

We are looking for outstanding bioinformatics/computational biology scientists to work in the analysis of cutting-edge high-throughput genomic data generated from autoimmune disease patients. The chosen candidates will be working in a collaborative environment with data analysts and clinical researchers focused on translational autoimmune disease research. We are seeking highly motivated individuals to implement genomic data analysis pipelines. The analysts will also be supported in the development of new tools that improve currently available methodology.

Our lab has a direct access to a large bioresource on autoimmune diseases, as well as a long-lasting collaboration with the HudsonAlpha Institute for Biotechnology (Huntsville, Alabama), an international leader on NGS applications.

One position is open for studies from the research lab and one position is open for research in IMIDomics, a recent a recent-spinoff from the VHIR. Successful applicants at each post will focus on the high-throughput molecular profiling of autoimmune diseases. Large-scale datasets on transcriptomics (RNASeq), epigenetics (array, methyl-Seq) and other molecular data from patients of this prevalent group of diseases will be generated and integrated. Our biomedical research questions will be centered on main challenges in precision medicine in autoimmune diseases including patient stratification and drug discovery. The postdocs will work in close collaboration both with expert genomic scientists and medical researchers.

Tasks:

  • Development of a data analysis pipeline for NGS and other omic technologies
  • Statistical association analysis and model construction
  • Integration or results with external high-volume biological knowledge
  • Data mining to link molecular profiles to clinically relevant phenotypes

Desired skills and expertise

  • PhD in Bioinformatics, Computational Biology, Systems Biology or closely related areas.
  • Strong experience in analysis next-generation sequencing data sets.
  • Excellent programming skills.
  • Familiarity with R would be an asset, as well as previous experience on immune-related diseases.
  • Ability to work independently, strong communication skills and ability to work with non-computational scientists.

Contract duration and other benefits

3 years, competitive salary. Option of further extension.

Interested candidates should submit a CV, a cover letter summarizing relevant experience and names and contacts of two referees.

Required information and contact

Applications including all relevant credentials should be sent to: e-mail: hr.grr.vhir(ELIMINAR)@gmail.com.